By Rob Sutter
About the Author:
Anyone who understands brain tumors in general sense can tell you a bit about glioblastoma. Seen as the deadly form of cancer in the brain, it is apparent that research is going to be done with this set in place. What are some of the methods that can prove useful in removing these tumors from the brain and for there to be results that will stand in the long term? It seems as though there are immune cells to consider but I did not realize that there were so many details.
According to an article on Medical News Today, it seems as though there are specialized immune cells that have been deactivated in these brain tumors. The University of Calgary's Hotchkiss Brain Institute and Southern Alberta Cancer Research Institute looked into these and applied clinical trials to the matter as well. It's not like there aren't treatments, as organizations like Voices against Brain Cancer can attest to. However, with a median survival of only 15 months, the treatments in question are not as effective as they probably should be.
What is it about these immune cells in regards to tumors in particular? The report went into detail about how microglia in the body could be put to use for the sake of helping the body prevent instances of injury of infection. Simply put, the cells in question come together to work as the brain's immune system, for lack of a better term. The way that they are able to operate is to detect stem cells that can play into tumor growth and eliminate them before development begins.
A study was done with mice in relation to the immune cells and how they can impact the tumors in the brain. Daily doses of a particular drug - dubbed amphotericin B - were implemented in order to help reactivate microglia. Keep in mind that AmpB was utilized in the past, not so much in terms of tumor treatment but fungal infections in the brain and spinal cord. Nonetheless, the drug was able to provide strong results in terms of the immune system following the study spoken about.
With this drug being put to use on a day to say basis, the mice that were utilized were able to see halted growth in terms of their tumors. The fact that the drug in question was able to help their natural defense mechanisms is a point that, in my opinion, cannot be overlooked. For quite some time, commonly utilized therapies in this field have not exactly been the most worthwhile. To me, though, I believe that it's because of these new findings that those who are afflicted will be helped that much more.
According to an article on Medical News Today, it seems as though there are specialized immune cells that have been deactivated in these brain tumors. The University of Calgary's Hotchkiss Brain Institute and Southern Alberta Cancer Research Institute looked into these and applied clinical trials to the matter as well. It's not like there aren't treatments, as organizations like Voices against Brain Cancer can attest to. However, with a median survival of only 15 months, the treatments in question are not as effective as they probably should be.
What is it about these immune cells in regards to tumors in particular? The report went into detail about how microglia in the body could be put to use for the sake of helping the body prevent instances of injury of infection. Simply put, the cells in question come together to work as the brain's immune system, for lack of a better term. The way that they are able to operate is to detect stem cells that can play into tumor growth and eliminate them before development begins.
A study was done with mice in relation to the immune cells and how they can impact the tumors in the brain. Daily doses of a particular drug - dubbed amphotericin B - were implemented in order to help reactivate microglia. Keep in mind that AmpB was utilized in the past, not so much in terms of tumor treatment but fungal infections in the brain and spinal cord. Nonetheless, the drug was able to provide strong results in terms of the immune system following the study spoken about.
With this drug being put to use on a day to say basis, the mice that were utilized were able to see halted growth in terms of their tumors. The fact that the drug in question was able to help their natural defense mechanisms is a point that, in my opinion, cannot be overlooked. For quite some time, commonly utilized therapies in this field have not exactly been the most worthwhile. To me, though, I believe that it's because of these new findings that those who are afflicted will be helped that much more.
About the Author:
Contact Voices Against Brain Cancer if you're looking for some additional information about brain tumor research.
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